In Microsoft Word, you can quickly create a custom layout "on te fly" by double-clicking anywhere on a page and typing or inserting a graphic. Your items do not need to be aligned in any way. You also don't need to pre-position the cursor using the Enter, tab or spacebar keys.
Consider using this feature for handouts, flyers or brainstorming/mindmapping sessions. Note that you must be in Print or Web Layout view (under the View menu).